important dates
Course fees
Early Registration
Students from University of Porto (UP): 50 Euros*
Others: 80 Euros*
Late Registration
Students from UP: 100 Euros*
Others: 160 Euros*
*Additional optional costs will be necessary if the participant wishes to include coffee-breaks, lunches and/or course dinner.
The registration fee includes the admission to the full-program of the International Intensive Course on Cancer Biology and the course material. Coffee-breaks, lunch and dinner are not included in the basic course fee.
Additional Optional Costs (ONLY available until 17th December 2017)
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10x Coffee Breaks: 36 Euros
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5x Buffet Lunches: 66 Euros OR alternatively FFUP has a canteen. For more information please see FFUP canteen prices.
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Meeting Dinner: 35 Euros
certificate of participation
Certificates of participation will be issued based on confirmation of participation in at least 80% of the lectures (corresponding to at least 16 lectures of the 20 available). Confirmation of participation will be based on signature on an attendance sheet, which will be available during each lecture.
Early Registration: until 30th November 2017
Late Registration: after 1st December 2017
Registration Deadline: 17th December 2017
Course date: 8th January to 12th January 2018
Course Objectives
The objective of this course is to provide an intense update on advances in cancer biology, from carcinogenesis to epidemiology, etiology and therapy. The course aims to provide a translational view of cancer, from basic science to clinical applications.
The course program will update participants on:
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Genetic and epigenetic alterations; tumour dynamics and hallmarks of cancer;
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Introduction to metakaryotic stem cells; biology and physiology of cancer cells;
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Epidemiology and etiology of cancer;
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Carcinogenic mechanisms and development of cancer;
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Therapy of cancer: from conventional therapies to novel approaches.
Duration of the course
The course comprises 20 lectures. Attendance is possible following registration and payment of a fee.
However, the course includes one conference open to the entire scientific community (free of charge) on the discovery of metakaryotic stem cells.
Lectures: 60 mins followed by 30 mins discussion; 4 lectures/day
Total duration of lectures: 30 hours
Teaching language: English only
Audience
The course is aimed mainly at international post-graduate students (master and PhD students), young researchers, post-doctoral researchers, oncologists and University lecturers. However, the course is open to the entire international scientific community at University level. Previous knowledge on oncobiology is highly recommended.
Certificates of participation
Certificates of participationwill be issued based on confirmation of participation in at least 80% of the lectures (corresponding to at least 16 lectures of the 20 available). Confirmation of participation will be based on signature on an attendance sheet, whichwill be available during each lecture.
WELCOME TO OPORTO
International Course on cANCER BIOLOGY
2018 edition
Organizing Committee
Person responsible for the course: Prof. M. Helena Vasconcelos, FFUP /IPATIMUP/i3S
M. Helena Vasconcelos, Ph.D.
Assistant Professor at FFUP and Leader of the Cancer Drug Resistance Group at IPATIMUP/i3S
Marilene Estanqueiro, Ph.D. student
Invited Assistant at FFUP
and Ph.D. student of the Cancer Drug Resistance Group at IPATIMUP/i3S
Hugo R. Caires, Ph.D.
Post-Doc of Cancer Drug Resistance Group at IPATIMUP/i3S
Cristina Xavier, Ph.D.
Post-Doc of Cancer Drug Resistance Group at IPATIMUP/i3S
Professor of Genetics, Toxicology and Biological Engineering at the MIT in USA
Manuel Sobrinho Simões, MD, Ph.D.
Jubilee Professor of Pathology of the Medical Faculty and Director of IPATIMUP
Manuel R. Teixeira, MD, Ph.D.
Director of Department of Genetics and Research Center at IPO-Porto and Guest Full Professor at ICBAS-UP
lecturers
Carmen Jerónimo, Ph.D.
Leader of the Cancer Biology and Epigenetics Group at IPO-Porto and Invited Associate Professor in Pathology and Molecular Genetics at ICBAS-UP
Natércia Teixeira, Ph.D.
Full Professor at FFUP, Sub-Director of FFUP and leader of the Drug Target and Biomarkers Research Group at UCIBIO-REQUMTE
Cecília Rodrigues, Ph.D.
Full Professor at Faculty of Pharmacy, University of Lisbon (FFUL) and Director at iMed.ULisboa
DAY 1 (January 8, Monday)
Genetic and epigenetic alterations, tumour dynamics and hallmarks
08,40h – Registration
09,00h – Welcome reception
09,30h - “Introduction: a synthesis of epidemiology, stem cell physiology, genetics, epigenetics and toxicology”
Prof. William Thilly, Professor of Genetics, Toxicology and Biological Engineering at theMassachusetts Institute of
Technology (MIT) in USA
11,00h - Coffee break
11,30h - “Tumour dynamics, heterogeneity and the hallmarks of cancer”
Prof. Manuel Sobrinho-Simões, Jubilee Professor of Pathology of the Medical Faculty and Director of the Institute of
Molecular Pathology and Immunology of the University of Porto (PATIMUP)
13,00h - Lunch break
14,00h – “Genetic alterations in sporadic and hereditary cancers”
Prof. Manuel Teixeira, Director of Department of Genetics and Research Center at IPO-Porto and Guest Full Professor at
ICBAS-UP
15,30h - Coffee break
16,00h – “Epigenetic alterations in cancers”
Prof. Carmen Jerónimo, Leader of the Cancer Biology and Epigenetics Group at the Portuguese Oncology Institute of
Porto (IPO Porto) and Invited Associate Professor in Pathology and Molecular Genetics at ICBAS-UP
17,30h - End session
DAY 2 (January 9, TUESDAY)
Introduction to metakaryotic stem cells; biology and physiology of cancer cells
09,30h – “Molecular biology /Altered pathways in cancer cells”
Prof. Natércia Teixeira, Full Professor at FFUP, Sub-Director of FFUP and leader of the Drug Target and Biomarkers
Research Group at UCIBIO-REQUMTE
11,00h – Coffee break
11,30h – “Identification of biomarkers of cancer and therapeutic targets”
Prof. Cecília Rodrigues, Full Professor at Faculty of Pharmacy, University of Lisbon (FFUL) and Director at iMed.ULisboa
13,00h - Lunch break
14,00h - “Physiological alterations in cancer and clinical implications”
Prof. Jorge Gonçalves, Full Professor of Pharmacology at FFUP and Researcher at the Center for Drug Discovery and
Innovative Medicines (MedInUP)
15,30h - Coffee break
16,00h – “Introduction to metakaryotic biology, morphology and physiology of stem cells of fetal/juvenile development and cancers”
Prof. William Thilly, Professor of Genetics, Toxicology and Biological Engineering at the Massachusetts Institute of
Technology (MIT) in USA
17,30h - End session
DAY 3 (January 10, WEDNESDAY)
Epidemiology and Etiology
09,30h – “History of mortality from cancers in the United States, 1900-2010”
Prof. William Thilly, Professor of Genetics, Toxicology and Biological Engineering at the Massachusetts Institute of
Technology (MIT) in USA
11,00h – Coffee break
11,30h – “Epidemiologic knowledge: impact on cancer policies and public health programs”
Prof. Henrique Barros, Full Professor of Epidemiology at the Faculty of Medicine of the University of Porto (FMUP),
President of the Institute of Public Health from the University of Porto and President of the International Epidemiological
Association
13,00h - Lunch break
14,00h – “Etiopathogenesis of cancer: gene environment interactions”
Prof. Fátima Carneiro, MD, PhD, Full Professor of Pathology (Medical Faculty of Porto), Head of Department of Anatomic
Pathology (Centro Hospitalar São João) and Senior Researcher at IPATIMUP/i3S
15,30h - Coffee break
16,00h - “Integrating knowledge on epidemiology, biology, pathology and therapy of cancer – clinical cases”
Prof. Rui Henrique, Director of Department of Pathology at IPO Porto and Invited Full Professor at ICBAS-UP
17,30h - CONFERENCE OPEN TO ALL SCIENTIFIC COMMUNITY:
“Discovery of metakaryotic stem cells of human organs, tumours and atherosclerotic plaques”
Doctor Elena V. Gostjeva, Research Scientist at the Department of Biological Engineering, Massachusetts Institute of
Technology (MIT) in USA
19,30h - COURSE DINNER
22,00h - End session
DAY 4 (January 11, THURSDAY)
Carcinogenic mechanisms and development of cancer
09,30h – “The relevance of the environment in carcinogenesis”
Prof. Raquel Soares, Full Professor at FMUP and Leader of Metabolism, nutrition & endocrinology Group at i3S
11,00h – Coffee break
11,30h – "Amended “two-stage” cancer model: required initiation and promotion events occur in mutator/hypermutable
normal metakaryotic stem cells and promotion events occur in initiated metakaryotic preneoplastic stem cells”
Prof. William Thilly, Professor of Genetics, Toxicology and Biological Engineering at the Massachusetts Institute of
Technology (MIT) in USA
13,00h - Lunch break
14,00h – “Molecular mechanisms of carcinogenesis”
Prof. Fernando Remião, Associate Professor at FFUP and Senior Researcher at UCIBIO/REQUIMTE
15,30h - Coffee break
16,00h - “Biomarkers of genotoxicity/DNA damage”
Prof. Nuno Oliveira, Assistant Professor with Aggregation, Faculty of Pharmacy, University of Lisbon (FFULisboa) -
Department of Toxicological and Bromatological Sciences and Researcher at iMed.ULisboa
17,30h - End session
DAY 5 (January 12, FRIDAY)
Therapy of cancer: from conventional therapies to novel approaches
09,30h - “From conventional to personalized therapy”
Prof. Ana Bela Sarmento, Associate Professor with Agregation at FMUC; Group Leader at CIMAGO; Investigator at
CNC.IBILI and Clinical Hematologist at CHUC
11,00h - Coffee break
11,30h - “Cancer Drug Resistance”
Prof. M. Helena Vasconcelos, Assistant Professor at FFUP and Leader of the Cancer Drug Resistance Group at
IPATIMUP/i3S
13,00h - Lunch break
14,00h - “Clinical trials: from the bench to the clinic”
Prof. Lúcio Lara Santos, Professor of Surgical Oncology at ICBAS-UP, Head of Experimental Pathology and Therapeutics Group and
member of Surgical Oncology Department of IPO-Porto
&
Dr. Júlio Oliveira, Medical Oncologist and Clinical Pharmacologistat IPO Porto and PhD student in Medical Sciences at ICBAS-UP
15,30h - Coffee break
16,00h - “Metakaryotic cancer stem cells are constitutively resistant to X-rays and present-day chemotherapies but sensitive
to many common drugs: proposal for treating cancers by killing all neoplastic metakaryotic stem cells”
Prof. William Thilly, Professor of Genetics, Toxicology and Biological Engineering at the Massachusetts Institute of
Technology (MIT) in USA
17,30h - Closing ceremony
17,45h - Port wine tasting
Course programme
Full Professor of Pharmacology and Researcher at the Center for Drug Discovery and Innovative Medicines (MedInUP) at FFUP
Henrique Barros , MD, Ph.D.
Full Professor of Epidemiology at FMUP and President of the Institute of Public Health from the University of Porto and President of the International Epidemiological Association
Fátima Carneiro, MD, Ph.D.
Full Professor of Pathology at FMUP, Head of Department of Anatomic Pathology, CHS-J and Senior Researcher at Ipatimup/i3S
Director of Department of Pathology at IPO Porto and Invited Full Professor at ICBAS-UP
Elena Gostjeva, Ph.D.
Research Scientist at the Department of Biological Engineering, MIT in USA
Raquel Soares, Ph.D.
Full Professor at FMUP and Leader of Metabolism, Nutrition & Endocrinology Group at i3S
Associated Professor at FFUP and Senior Researcher at UCIBIO/REQUIMTE
Nuno Oliveira, Ph.D.
Assistant Professor with Aggregation, Faculty of Pharmacy, University of Lisbon (FFULisboa) - Department of Toxicological and Bromatological Sciences and Researcher at iMed.ULisboa
Ana Bela Sarmento, MD, Ph.D.
Associate Professor with Agregation at FMUC; Group Leader at CIMAGO; Investigator at CNC.IBILI and Clinical Hematologist at CHUC
Assistant Professor at FFUP and Leader of the Cancer Drug Resistance Group at IPATIMUP/i3S
Lúcio Lara Santos, MD, Ph.D.
Professor of Surgical Oncology at ICBAS-UP, Head of Experimental Pathology and Therapeutics Group and member of Surgical Oncology Department of IPO-Porto
Júlio Oliveira, MD
Medical Oncologist and Clinical Pharmacologist at IPO Porto and
PhD student in Medical Sciences at ICBAS-UP
Course registration
location & venue
The International Intensive Course on Cancer Biology will be held at the Faculty of Pharmacy of the University of Porto (FFUP).
Address: Rua de Jorge Viterbo Ferreira, 228, 4050-313 - Porto, Portugal
GPS coordinates: 41°08'51.3"N 8°37'26.1"W
Lectures: Salão Nobre of ICBAS/FFUP complex
HOW TO GET HERE
Faculty of Pharmacy Porto University (FFUP)
Rua de Jorge Viterbo Ferreira, 228
4050-313 - Porto
PORTUGAL
Telephone: +351 220 428 500
Fax: +351 226 093 390
Web: http://www.ff.up.pt
For further information please contact:
Professor Helena Vasconcelos: helena.vasconcelos@ff.up.pt
International Intensive Course on Cancer biology 2018 edition
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Course secretariat
